-
Patient factors
- Age
- Sex,
- Comorbid physical illness
- Previous response
-
Tolerability
-
Symptomatology
- Sleep problems (mirtazepine)
- Anxiety symptoms (SSRI/imipramine).
- OCD symptoms (SSRI/clomipramine).
- Risk of suicide (avoid TCAs).
-
Clinician familiarity
Treatments > Biological > Medication > Choice